Computed tomography volumetric analysis for predicting postoperative lung function for segmentectomy. (25th July 2022)

• Record Type: Journal Article
• Authors: Bae, Seon Yong; Lee, Haeju; Na, Kwon Joong; Na, Bubse; Park, Samina; Park, In Kyu; Kang, Chang Hyun; Kim, Young Tae
• Is Part Of: Interactive cardiovascular and thoracic surgery. Volume 35:Number 2(2022)
• Publication Date: 2022-07-25
• Subjects: Computed tomography -- Lung cancer -- Lung resection surgery -- Predictive postoperative lung function; Chest -- Surgery -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.1
• DOI: 10.1093/icvts/ivac195
• Languages: English
• ISSNs: 1569-9293

Abstract

Abstract: OBJECTIVES: We compared the computed tomographic (CT) volumetric analysis and anatomical segment counting (ASC) for predicting postoperative forced expiratory volume in 1 s (FEV1 ) and diffusing capacity for carbon monoxide (DLCO ) in patients who had segmentectomy for early-stage lung cancer. METHODS: A total of 175 patients who had segmentectomy for lung cancer and had postoperative pulmonary function test were included. CT volumetric analysis was performed by software, which could measure total lung and target segment volume from CT images. ASC and CT volumetric analysis were used to determine predicted postoperative (PPO) values and the concordance and difference of these values were assessed. The relationship between PPO values and actual postoperative values was also investigated. RESULTS: The PPO-FEV1 and PPO-DLCO showed high concordance between 2 methods (concordance correlation coefficient = 0.96 for PPO-FEV1 and 0.95 for PPO-DLCO ). There was no significant difference between PPO values as determined by 2 methods ( P = 0.53 for PPO-FEV1, P = 0.25 for PPO-DLCO ) and actual postoperative values [ P = 0.77 (ASC versus actual) and P = 0.20 (CT versus actual) for FEV1 ; P = 0.41 (ASC versus actual) and P = 0.80 (CT versus actual) for DLCO ]. We subdivided the patients according to poor pulmonary function test, the number of resected segments and the location of the resected lobe. All subgroup analyses revealed no significant difference between PPO values and actual postoperative values. CONCLUSIONS: Both CT volumetric analysis and ASC showed high predictability for actual postoperative FEV1 and DLCO in segmentectomy. Abstract : Lung cancer is the leading cause of cancer-related mortality worldwide, accounting for one out of every 5 deaths [1].