Green Synthesis and Layer-by-Layer Assembly of Amino-Functionalized Graphene Oxide/Carboxylic Surface Modified Trimetallic Nanoparticles Nanocomposite for Label-Free Electrochemical Biosensing. Issue 12 (1st January 2019)

• Record Type: Journal Article
• Authors: Sharifuzzaman, Md.; Barman, Sharat Chandra; Rahman, M. Toyabur; Zahed, Md. Abu; Xuan, Xing; Park, Jae Y.
• Is Part Of: Journal of the Electrochemical Society. Volume 166:Issue 12(2019)
• Page Start: B983
• Page End: B993
• Publication Date: 2019-01-01
• Subjects: Sensors -- COOH-AgPtPd -- Layer-by-Layer assembly -- H2O2 -- PSA -- Sodium periodate -- NH2-rGO; Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/2.0821912jes
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : In this context, a novel, scalable and facile method for the green synthesis of graphene oxide (GO) to facilitate effective and safe oxidation of graphite using sodium periodate (NaIO4 ) is demonstrated. The optimized value of the oxidizing agent NaIO4 ensured effective oxidation, minimized defects on sp 2 C-C plane (ID /IG = 0.645) and increased C/O atomic ratio of ∼5.146. Subsequently, we successfully synthesized the amino-functionalized reduced graphene oxide (NH2 -rGO) and carboxylic surface modified AgPtPd (COOH-AgPtPd) trimetallic nanoparticles (TNPs), in order to fabricate a label-free electrochemical sensing platform using the conventional immersive layer-by-layer (LBL) assembly. The superior synergetic effect between LBL-assembled NH2 -rGO and COOH-AgPtPd (COOH-AgPtPd/NH2 -rGO) significantly boosts the electron transfer rate of the electrode as well as electrocatalytic efficiency. Therefore, the as-prepared COOH-AgPtPd/NH2 -rGO nanocomposite-based sensing material was first employed for nonenzymatic electrochemical detection of H2 O2, with a low detection limit of 0.2 nM. Moreover, COOH-AgPtPd/NH2 -rGO nanocomposite can also be utilized as a sensing platform for label-free accurate electrochemical detection of prostate-specific antigen (PSA) over a large linear range of 4 fg mL −1 to 300 ng mL −1, with an ultra-low detection limit (LOD) of 4 fg mL −1 .