Design Automation and Testing of MEDA-Based Digital Microfluidic Biochips: A Brief Survey. Issue 5 (2nd September 2020)

• Record Type: Journal Article
• Authors: Howladar, Pampa; Roy, Pranab; Rahaman, Hafizur
• Is Part Of: IETE journal of research. Volume 66:Issue 5(2020)
• Page Start: 662
• Page End: 676
• Publication Date: 2020-09-02
• Subjects: Digital Microfluidics -- Microelectrode-dot-array (MEDA) architecture -- EWOD -- Synthesis -- Testing -- FPLOC -- Lab on CMOS; Electronics -- Periodicals; Telecommunication -- Periodicals; Electronics; Telecommunication; Periodicals; 621.38
• DOI: 10.1080/03772063.2018.1516520
• Languages: English
• ISSNs: 0377-2063

Abstract

ABSTRACT: In recent years, application of digital microfluidic biochips (DMFBs) in an extended range, suffers from a few limitations namely (a) flexibility on droplet size (b) requirement of special fabrication process (c) need for integrated sensor systems for real-time detection. To overcome these challenging issues, a DMFB based new advanced microelectrode dot array architecture (MEDA) with advanced characteristics such as field programmability, higher reconfigurability and scalability has been introduced. This paper provides a comprehensive survey of MEDA-based DMFBs, a review on fluidic level synthesis as well as chip-level design to solve problems such as malfunctioning microelectrodes, droplet classification, system automation, biomedical detection and surface flatness testing, followed by a brief description on fault Modeling, testing and error recovery technique on MEDA architecture. Finally, the survey concludes with suggestions for future advancement possibilities in the areas of development of MEDA-based Biochips.