Green Synthesis of Reduced Graphene Oxide Decorated with Few-Layered MoS2-Nanoroses and Au/Pd/Ag Trimetallic Nanoparticles for Ultrasensitive Label-Free Immunosensing Platforms. Issue 4 (1st January 2019)

• Record Type: Journal Article
• Authors: Sharifuzzaman, Md.; Barman, Sharat Chandra; Zahed, Md. Abu; San, Nah Joong; Park, Jae Yeong
• Is Part Of: Journal of the Electrochemical Society. Volume 166:Issue 4(2019)
• Page Start: B249
• Page End: B257
• Publication Date: 2019-01-01
• Subjects: Electroanalytical Electrochemistry -- Green reduced graphene oxide -- Molybdenum disulfide nanoroses -- L-proline assisted Au@Pd@Ag -- Label-free platform -- Ultrasensitive immunosensing platform -- Ochratoxin A; Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/2.0861904jes
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : The conventional synthetic methods for graphene oxide are based on the reaction of graphite with mixed strong oxidants, which involves the risk of explosion and toxic gases. Herein, we report a facile, safe, and green method to synthesize green graphene oxide (denoted as gGO) using sodium periodate as an effective oxidizing agent feature with lower Raman intensity (ID /IG = 0.65) and higher C/O atomic ratio ( ∼ 5.15). We also discuss the mechanism underlying the direct growth of MoS2 nanoroses (MoS2 -NRs) on the in situ synthesized green reduced graphene oxide (grGO), in which the MoS2 -NRs are assembled from few-layered MoS2 nanosheets. Due to the highly exposed active edge sites of MoS2 -NRs and good electrical coupling with the underlying grGO, the resulting grGO/MoS2 -NRs nanocomposite exhibits excellent electrocatalytic activity. Furthermore, the addition of L-proline assisted Au/Pd/Ag trimetallic nanoparticles to the nanocomposite provide a suitable label-free platform for direct antibody immobilization and increase the effective surface area. The as-prepared grGO/MoS2 -NRs/AuPdAg nanocomposite was employed as a label-free immunosensing platform for the ultrasensitive detection of ochratoxin A, a food mycotoxin. The proposed immunosensor exhibits an excellent high detection range from 10 fg mL −1 to 150 ng mL −1 and limit of detection (LOD) of 5 fg mL −1 (S/N = 3).