Function of PoLAE2, a laeA homolog, in appressorium formation and cAMP signal transduction in Pyricularia oryzae. Issue 11 (1st November 2020)

• Record Type: Journal Article
• Authors: Prajanket, Pradabrat; Vu, Kim-Chi Thi; Arai, Jun; Sornkom, Worawan; Abe, Ayumi; Sone, Teruo
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 84:Issue 11(2020)
• Page Start: 2401
• Page End: 2404
• Publication Date: 2020-11-01
• Subjects: LaeA -- appressorium formation -- signal transduction -- cAMP; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2020.1801379
• Languages: English
• ISSNs: 0916-8451

Abstract

ABSTRACT: A novel homolog of laeA, a global regulatory gene in filamentous fungi, was identified from Pyricularia oryzae . A deletion mutant of the homolog ( PoLAE2 ) exhibited lowered intracellular cAMP levels, and decreased appressorium formation on non-host surface; the decrease was recovered using exogenous cAMP and IBMX, indicating that PoLAE2 deletion affected the cAMP signaling pathway.