Additive Manufacturing of Microreservoir Devices for Oral Drug Delivery Using an Acculas BA-30 Micro-Stereolithography Instrument: A Feasibility Study. Issue 9 (1st January 2019)

• Record Type: Journal Article
• Authors: Vaut, Lukas; Jensen, Kristian E.; Tosello, Guido; Khosla, Ajit; Furukawa, Hidemitsu; Boisen, Anja
• Is Part Of: Journal of the Electrochemical Society. Volume 166:Issue 9(2019)
• Page Start: B3257
• Page End: B3263
• Publication Date: 2019-01-01
• Subjects: Sensors -- 3D printing -- Microfabricated devices -- Oral drug delivery; Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/2.0421909jes
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : Within the research and the development of protective carrier platforms intended for oral drug delivery, polymeric microreservoir devices with sizes around 300 μm have been proposed as a delivery system capable of unidirectional drug release. So far, microreservoir devices have been fabricated with simple shapes by means of high-throughput fabrication methods. In this feasibility study, state-of-the-art micro-stereolithography 3D printing is used for the fabrication of various microreservoir geometries. Scanning electron microscopy characterization and conducted resolution tests demonstrated the capability of the used technology and unveils challenges and opportunities associated with the proposed fabrication process.