S253: THE SHEDDASE DOMAIN OF ADAM10 AUGMENTS THE INTERACTION OF LEUKEMIA CELLS WITH THE BONE MARROW NICHE IN VIVO AS SHOWN BY RECONSTITUTING PDX LEUKEMIA CELLS WITH CRISPR-CAS9-INDUCED KNOCKOUT. (23rd June 2022) - Schmid, J. P.; Bahrami, E.; Becker, M.; Jayavelu, A. K.; Wirth, A.-K.; Jurinovic, V.; Öllinger, R.; Rad, R; Vick, B.; Mann, M.; Herold, T.; Jeremias, I.