Natural Compounds as Next-Generation Herbicides. Issue 3 (30th April 2014)

• Record Type: Journal Article
• Authors: Dayan, Franck E.; Duke, Stephen O.
• Is Part Of: Plant physiology. Volume 166:Issue 3(2014)
• Page Start: 1090
• Page End: 1105
• Publication Date: 2014-04-30
• Subjects: Plant physiology -- Periodicals; Botany -- Periodicals; Periodicals; Electronic journals; 571.2
• DOI: 10.1104/pp.114.239061
• Languages: English
• ISSNs: 0032-0889

Abstract

Abstract : Natural products are an important resource in the discovery of herbicides . Abstract: Herbicides with new modes of action (MOA s) are badly needed due to the rapidly evolving resistance to commercial herbicides, but a new MOA has not been introduced in over 20 years. The greatest pest management challenge for organic agriculture is the lack of effective natural product herbicides. The structural diversity and evolved biological activity of natural phytotoxins offer opportunities for the development of both directly used natural compounds and synthetic herbicides with new target sites based on the structures of natural phytotoxins. Natural phytotoxins are also a source for the discovery of new herbicide target sites that can serve as the focus of traditional herbicide discovery efforts. There are many examples of strong natural phytotoxins with MOA s other than those used by commercial herbicides, which indicates that there are molecular targets of herbicides that can be added to the current repertoire of commercial herbicide MOA s.