Aortic intima-media thickness in neonates exposed to early-onset preeclampsia. (December 2020)

• Record Type: Journal Article
• Authors: Oikonomou, Nikoleta; Fouzas, Sotirios; Gkentzi, Despoina; Dimitriou, Gabriel; Karatza, Ageliki A.
• Is Part Of: Early human development. Volume 151(2020)
• Publication Date: 2020-12
• Subjects: Preeclampsia -- Aortic intima-media thickness -- Atherosclerosis; Fetus -- Periodicals; Neonatology -- Periodicals; Prenatal influences -- Periodicals; 612.65
• DOI: 10.1016/j.earlhumdev.2020.105166
• Languages: English
• ISSNs: 0378-3782

Abstract

Abstract: Aortic intima-media thickness (aIMT) and its ratio to aortic diameter (aIMT/AoD) were measured on the second and fifth postnatal day in 39 neonates exposed to early-onset preeclampsia and 39 controls. Both aIMT and aIMT/AoD were higher in neonates exposed to preeclampsia ( P < 0.001 for all comparisons). Highlights: Early-onset preeclampsia is associated with structural aortic changes at birth. Exposed newborns have increased aortic intima-media thickness (aIMT). aIMT remains increased after correction for the diameter of the vessel. These changes are consistent up to the fifth day of life.