Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis. (4th March 2016)

• Record Type: Journal Article
• Authors: Tolbert, M.K.; Gookin, J.L.
• Is Part Of: Journal of veterinary internal medicine. Volume 30:Number 2(2016:Mar./Apr.)
• Page Start: 516
• Page End: 526
• Publication Date: 2016-03-04
• Subjects: Diarrhea -- Protozoa -- Trichomonas -- Trichomonas vaginalis; Veterinary medicine -- Periodicals; 636.0896
• DOI: 10.1111/jvim.13920
• Languages: English
• ISSNs: 0891-6640

Abstract

Abstract : Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the infection, we still know very little about how this parasite causes diarrhea. With increasing recognition of resistance of trichomonosis to treatment with 5‐nitroimidazole drugs, new treatment strategies based on an understanding of disease pathogenesis are needed. In this review, lessons learned from the pathogenesis of venereal trichomonosis in people and cattle are applied to clinical observations of trichomonosis in cats in effort to generate insight into areas where further research may be beneficial.