Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD. Issue 1 (19th June 2018)

• Record Type: Journal Article
• Authors: Picoraro, Joseph A; Lee, Dale; Heller, Caren A; Weaver, Alandra; Hyams, Jeffrey S; Conklin, Laurie S; Otley, Anthony; Ziring, David; Kugathasan, Subra; Rosh, Joel R; Mulberg, Andrew; Denson, Lee A; Kappelman, Michael D; Grossman, Andrew B; Bousvaros, Athos; Park, K T
• Is Part Of: Inflammatory bowel diseases. Volume 25:Issue 1(2019)
• Page Start: 27
• Page End: 32
• Publication Date: 2018-06-19
• Subjects: Crohn's disease -- clinical trial -- pediatrics -- off-label use -- ulcerative colitis; Inflammatory bowel diseases -- Periodicals; Colitis, Ulcerative -- Periodicals; Crohn Disease -- Periodicals; Inflammatory Bowel Diseases -- Periodicals; 616.344
• DOI: 10.1093/ibd/izy205
• Languages: English
• ISSNs: 1078-0998

Abstract

Abstract: The Crohn's & Colitis Foundation has facilitated transformational research in pediatric inflammatory bowel disease (IBD), through the RISK and PROTECT studies, that has laid the groundwork for a comprehensive understanding of molecular mechanisms of disease and predictors of therapeutic response in children. Despite these advances, children have lacked timely and informed access to the latest therapeutic advancements in IBD. The Crohn's & Colitis Foundation convened a Pediatric Resource Organization for Kids with Inflammatory Intestinal Diseases (PRO-KIIDS) Clinical Innovations Meeting at the inaugural Crohn's and Colitis Congress in January 2018 to devise how to advance the care of children with IBD. The working group selected 2 priorities: (1) accelerating therapies to children with IBD and (2) stimulating investigator-initiated research while fostering sustainable collaboration; and proposed 2 actions: (a) the convening of a task force to specifically address how to accelerate pharmacotherapies to children with IBD and (b) the funding of a multicenter clinical and translational research study that incorporates the building of critical research infrastructure.