Constrictive pericarditis following mRNA COVID-19 vaccination in a patient with systemic sclerosis. Issue 2 (August 2022)

• Record Type: Journal Article
• Authors: Misumi, Ikuo; Ogata, Aki; Fukuda, Koichiro; Sato, Koji; Nagano, Miwa; Usuku, Hiroki; Tsujita, Kenichi
• Is Part Of: Journal of cardiology cases. Volume 26:Issue 2(2022)
• Page Start: 97
• Page End: 100
• Publication Date: 2022-08
• Subjects: Constrictive pericarditis -- Coronavirus disease 2019 vaccine -- Systemic sclerosis -- Steroid; Cardiology -- Periodicals; Cardiovascular Diseases -- Case Reports; Cardiovascular Diseases -- Periodicals; Cardiology -- Case Reports; Cardiology -- Periodicals; Cardiology; Electronic journals; Periodicals; 616.12
• DOI: 10.1016/j.jccase.2022.03.014
• Languages: English
• ISSNs: 1878-5409

Abstract

Abstract: A 59-year-old man with systemic sclerosis and interstitial pneumonia was referred to our department because he developed dyspnea and leg edema after receiving a first shot of coronavirus disease 2019 (COVID-19) vaccine. Transthoracic echocardiography showed moderate pericardial effusion with conspicuous fibrin deposition. Prednisolone was increased from 6 mg/day for systemic sclerosis to 20 mg/day. Thereafter, pericardial effusion gradually decreased. However, his symptoms continued. Transthoracic echocardiography showed disappearance of pericardial effusion and thickened pericardium. Pulsed-wave and tissue Doppler echocardiography revealed that the patient suffered from newly developed constrictive pericarditis. COVID-19 vaccination might have contributed to acute pericarditis and subsequent constrictive pericarditis in the present case of systemic sclerosis and pulmonary fibrosis. Learning objective: Incidence of adverse effects after coronavirus disease 2019 vaccination is rare. The present case suggests the risk of pericarditis that may lead to constrictive pericarditis.