Blastic Plasmacytoid Dendritic Cell Neoplasm Following Acquired Erythropoietic Protoporphyria. Issue 4 (1st October 2017)

• Record Type: Journal Article
• Authors: Krause, John R.; Baugh, Laura; Swink, Alicia; Burch, Micah
• Is Part Of: Proceedings. Volume 30:Issue 4(2017)
• Page Start: 450
• Page End: 451
• Publication Date: 2017-10-01
• Subjects: Medicine -- Periodicals; Medicine; Medicine -- Periodicals; Periodicals; Electronic journals; 616.005
• DOI: 10.1080/08998280.2017.11930225
• Languages: English
• ISSNs: 0899-8280

Abstract

Abstract : A 56-year-old Texas rancher with a prior diagnosis of acquired erythropoietic protoporphyria secondary to an underlying myelodysplastic disorder developed an uncommon tumor, blastic plasmacytoid dendritic cell neoplasm (BPDCN). During his initial disease, analysis revealed a TET2 mutation, which is the most common mutation associated with BPDCN. This article discusses this unusual hema-topoietic neoplasm, the possible evolution from erythropoietic protoporphyria, and the underlying myelodysplastic process.