A Rare Hemoglobin Variant, Hb Belliard. Issue 2 (1st April 2017)

• Record Type: Journal Article
• Authors: Murthy, Stacey; Benavides, Raul
• Is Part Of: Proceedings. Volume 30:Issue 2(2017)
• Page Start: 184
• Page End: 185
• Publication Date: 2017-04-01
• Subjects: Medicine -- Periodicals; Medicine; Medicine -- Periodicals; Periodicals; Electronic journals; 616.005
• DOI: 10.1080/08998280.2017.11929577
• Languages: English
• ISSNs: 0899-8280

Abstract

Abstract : There are many documented variants of hemoglobin; however, other than a limited number (such as sickle cell disease), very few are known to have any clinical significance. As advances in detection and identification continue through gel electrophoresis, capillary electrophoresis, and DNA sequencing, more rare variants are identified. Without case reporting, the significance of these variants will remain unknown or continue to be thought of as insignificant. Here we report a rare hemoglobin variant, Hb Belliard, which was detected in a 68-year-old Indian immigrant to the United States. He presented with elevated hemoglobin and was found to have a unique peak on capillary electrophoresis. The specimen was sent for sequencing and was subsequently found to have Hb Belliard. Currently, Hb Belliard is thought to be insignificant.