Flecainide toxicity in renal failure. Issue 3 (3rd July 2018)

• Record Type: Journal Article
• Authors: Subedi, Rogin; Dean, Ryan K.; Chaudhary, Arbind; Szombathy, Tamas
• Is Part Of: Proceedings. Volume 31:Issue 3(2018)
• Page Start: 328
• Page End: 330
• Publication Date: 2018-07-03
• Subjects: Flecainide toxicity -- renal failure -- ventricular tachycardia; Medicine -- Periodicals; Medicine; Medicine -- Periodicals; Periodicals; Electronic journals; 616.005
• DOI: 10.1080/08998280.2018.1463042
• Languages: English
• ISSNs: 0899-8280

Abstract

ABSTRACT: Flecainide, a class Ic antiarrhythmic, is used for the prevention of paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation/flutter, and sustained ventricular tachycardia. Flecainide is primarily metabolized by the liver and to a lesser extent (30%) is excreted unchanged in the kidney. We present a case of flecainide toxicity in the setting of renal impairment that was successfully treated with intravenous sodium bicarbonate.