COVID-19 vaccine and boosted immunity: Nothing ad interim to do?. Issue 48 (10th November 2020)

• Record Type: Journal Article
• Authors: Roncati, Luca; Vadalà, Maria; Corazzari, Veronica; Palmieri, Beniamino
• Is Part Of: Vaccine. Volume 38:Issue 48(2020)
• Page Start: 7581
• Page End: 7584
• Publication Date: 2020-11-10
• Subjects: Coronavirus Disease 2019 (COVID-19) -- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) -- Corynebacterium parvum (C. parvum) -- Propionibacterium acnes (P. acnes) -- Cutibacterium acnes (C. acnes) -- Bacillus Calmette-Guérin (BCG) -- Hyaluronic acid -- cluster of differentiation 44 (CD44) -- T helper 1 (Th1) -- T helper 2 (Th2) -- Vaccine; Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2020.10.013
• Languages: English
• ISSNs: 0264-410X

Abstract

Abstract: Today, Coronavirus Disease 2019 (COVID-19) is a global public health emergency and vaccination measures to counter its diffusion are deemed necessary. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of the disease, unleashes a T-helper 2 immune response in those patients requiring intensive care. Here, we illustrate the immunological mechanism to train the immune system towards a more effective and less symptomatic T-helper 1 immune response, to be exploited against SARS-CoV-2.