Association of disease duration and sensorimotor function in type 2 diabetes mellitus: beyond diabetic peripheral neuropathy. (1st October 2020)

• Record Type: Journal Article
• Authors: Khan, Neha; Ahmad, Irshad; Noohu, Majumi M.
• Is Part Of: Somatosensory & motor research. Volume 37:Number 4(2020)
• Page Start: 326
• Page End: 333
• Publication Date: 2020-10-01
• Subjects: Sensory function -- vibration sense -- proprioception -- balance -- postural sway -- reaction time; Skin -- Innervation -- Periodicals; Somesthesia -- Periodicals; Perceptual-motor processes -- Periodicals; 573.85
• DOI: 10.1080/08990220.2020.1830757
• Languages: English
• ISSNs: 0899-0220

Abstract

Abstract: Purpose: The aim of the study is to assess association of the duration of diabetes and vibration, proprioception, muscle strength, reaction time and balance measures in people with type 2 diabetes mellitus (DM) without peripheral neuropathy. Methods: Forty-seven type 2 diabetics without peripheral neuropathy and 23 healthy controls were recruited for the study. Patients with type 2 DM were further classified into 23 patients who suffered from diabetes for less than 5 years (<5yrDM) and 24 patients who had diabetes for 5 years and above (≥5yrDM). All participants were assessed for Michigan neuropathy screening instrument (MNSI), vibration perception threshold (VPT), proprioception, muscles strength, centre of pressure (COP) range, COP sway and reaction time. Results: ≥5yrDM patients were found to significantly differ from healthy control in MNSI score ( p ≤ 0.013), VPT score ( p ≤ 0.002), reaction time ( p ≤ 0.018), COP range ( p ≤ 0.005) and COP sway ( p ≤ 0.027). A significant difference was found only in reaction time ( p < 0.002) except in the back direction ( p = 0.089), and COP range ( p ≤ 0.016) except in the front ( p = 0.101) and right direction ( p = 0.085) between <5yrDM patients and healthy controls. Conclusions: ≥5yrDM patients exhibit a subtle deterioration in VPT, reaction time, and balance measure while <5yr DM patients were impaired only in COP range and reaction time when compared with healthy control.