A Review of Intraocular Pressure (IOP) and Axial Myopia. (9th July 2022)

• Record Type: Journal Article
• Authors: Zhang, Dongyan; Wang, Liyin; Jin, Le; Wen, Yingying; Zhang, Xuhong; Zhang, Liyue; Zhu, Hong; Wang, Ziyu; Yu, Xin; Xie, Chen; Tong, Jianping; Shen, Ye
• Other Names: Patel Sudhir Academic Editor.
• Is Part Of: Journal of ophthalmology. Volume 2022(2022)
• Publication Date: 2022-07-09
• Subjects: Ophthalmology -- Periodicals; Eye Diseases; Ophthalmology; Ophthalmology; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 617.7
• DOI: 10.1155/2022/5626479
• Languages: English
• ISSNs: 2090-004X

Abstract

Abstract : The pathogenesis of myopia is driven by genetic and environmental risk factors. Accommodation not only alters the curvature and shape of the lens but also involves contraction of the ciliary and extraocular muscles, which influences intraocular pressure (IOP). Scleral matrix remodeling has been shown to contribute to the biomechanical susceptibility of the sclera to accommodation-induced IOP fluctuations, resulting in reduced scleral thickness, axial length (AL) elongation, and axial myopia. The rise in IOP can increase the burden of scleral stretching and cause axial lengthening. Although the accommodation and IOP hypotheses were proposed long ago, they have not been validated. This review provides a brief and updated overview on studies investigating the potential role of accommodation and IOP in myopia progression.