Effects of Atrazine on Reproductive Health of Nondiabetic and Diabetic Male Rats. (28th October 2014)

• Record Type: Journal Article
• Authors: Jestadi, Dinesh Babu; Phaniendra, Alugoju; Babji, Undru; Shanmuganathan, Bhavatharini; Periyasamy, Latha
• Other Names: Fetoui Hamadi Academic Editor.
• Is Part Of: ISRN obstetrics and gynecology. Volume 2014(2014)
• Publication Date: 2014-10-28
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Pregnancy Complications; Genital Diseases, Female; Gynecology; Obstetrics; Electronic journals; Periodical; Periodicals; Fulltext; Internet Resources; Periodicals; 618.2
• DOI: 10.1155/2014/676013
• Languages: English
• ISSNs: 2090-4436

Abstract

Abstract : The aim of the present study was to investigate the effects of low dose of atrazine on reproductive system of male Wistar rats. 16 rats were divided into four groups of four animals each. Group I (nondiabetic) and group III (diabetic) animals served as controls that received safflower oil (300 μ L/kg bw/day), respectively. Group II (nondiabetic) and group IV (diabetic) animals received atrazine (300 μ g/kg bw/day). Nonsignificant decrease in the activities of antioxidant and steroidogenic enzymes and sperm parameters suggests that atrazine did not produce any effect on reproductive system of rats. Histological findings also revealed that atrazine at a dose of 300 μ g/kg bw did not produce any testicular toxic effects in nondiabetic and diabetic atrazine treated rats. Low dose of atrazine did not show reproductive toxicity in rats. To know the effects of atrazine in diabetic rats further studies have to be carried out with increased concentration of atrazine.