Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction. (15th June 2016)

• Record Type: Journal Article
• Authors: Tang, Junmei; Han, Yuemei; Chen, Hao; Lin, Quankui
• Other Names: Zhao Weifeng Academic Editor.
• Is Part Of: International journal of polymer science. Volume 2016(2016)
• Publication Date: 2016-06-15
• Subjects: Polymers -- Periodicals; Polymers; Periodicals; 547.7
• DOI: 10.1155/2016/8458752
• Languages: English
• ISSNs: 1687-9422

Abstract

Abstract : Poly(dimethylsiloxane) silicones have found many applications in biomedical devices, whereas their surface hydrophobicity always brings about unexpected bioadhesion, causing complications of the implanted biomedical devices. In this work, surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to generate PEG brushes on silicone surface, obtaining highly hydrophilic surface coatings. Such PEG brush coated silicone presents excellent antifouling to protein, cells, and bacteria, which may have great potential in implantable biomaterial surface modifications.