Leiomyosarcoma and Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary. (2nd July 2017)

• Record Type: Journal Article
• Authors: Pongsuvareeyakul, Tip; Sukpan, Kornkanok; Chaicharoen, Somjet; Khunamornpong, Surapan
• Other Names: Tot Tibor Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2017(2017)
• Publication Date: 2017-07-02
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2017/7907359
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : The occurrence of malignant transformation in mature cystic teratoma of the ovary is rare, with squamous cell carcinoma being the most common histologic type. Sarcomatous transformation has been rarely described in the literature. We present a case of leiomyosarcoma with a minor component of squamous cell carcinoma arising in mature cystic teratoma of ovary in a 65-year-old woman. The malignant tumor showed two distinct components of sarcomatous and invasive epithelial elements, which were confirmed by immunostaining. To our knowledge, only four cases of leiomyosarcoma in ovarian mature cystic teratoma have been reported and this is a unique case report of leiomyosarcoma and squamous cell carcinoma arising in a mature cystic teratoma of ovary.