Localized Castleman's Disease in the Breast in a Young Woman. (17th March 2016)

• Record Type: Journal Article
• Authors: Parra-Medina, Rafael; Guio, José Ismael; López-Correa, Patricia
• Other Names: Kulka Janina Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2016(2016)
• Publication Date: 2016-03-17
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2016/8413987
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : Castleman's disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.