Choroidal effusion: a rare and unusual complication of daratumumab. Issue 8 (1st August 2022)

• Record Type: Journal Article
• Authors: Singh, Aditi; Bazzi, Talal; Lebovic, Daniel; Demirci, Hakan
• Is Part Of: BMJ case reports. Volume 15:Issue 8(2022)
• Publication Date: 2022-08-01
• Subjects: Haematology (drugs and medicines) -- Immunological products and vaccines -- Eye -- Drugs and medicines -- Cancer - see Oncology; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2022-249735
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Daratumumab-containing regimens are an effective treatment for advanced cases of multiple myeloma. Overall, daratumumab has a favourable safety profile, although rare side effects can occur. Rare side effects of daratumumab include choroidal effusion. Patients who begin to experience symptoms such as eye swelling, vision changes, eye discharge and blurry vision should undergo urgent ophthalmological evaluation and their daratumumab infusions held.