Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children. (23rd April 2017)

• Record Type: Journal Article
• Authors: Li, Zhuoying; Han, Dong; Jiang, Jie; Chen, Jia; Tian, Lang; Yang, Zuocheng
• Other Names: Rennert Gad Academic Editor.
• Is Part Of: Disease markers. Volume 2017(2017)
• Publication Date: 2017-04-23
• Subjects: Diagnosis -- Periodicals; Biochemical markers -- Periodicals; Pathology -- Periodicals; 616
• DOI: 10.1155/2017/2960502
• Languages: English
• ISSNs: 0278-0240

Abstract

Abstract : Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions. PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki diseases (KD) is still unclear. In our study, we examined the PECAM-1 gene polymorphisms in 44 KD patients and 59 healthy children and revealed the correlation of PECAM-1 gene polymorphisms in KD children with and without coronary artery lesions (CAL).