Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location. (1st July 2014)

• Record Type: Journal Article
• Authors: Wyn, Inez; Debiec-Rychter, Maria; Van Cleynenbreugel, Ben; Sciot, Raf
• Other Names: Cao Dengfeng Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2014(2014)
• Publication Date: 2014-07-01
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2014/871530
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : We report the unusual occurrence of a cellular angiofibroma in prostatic tissue. In this case, a 84-year-old man presented in the emergency room with urinary retention. Ultrasound revealed an enlarged prostate, which was suggestive for benign prostatic hyperplasia. The patient was treated with a Millin retropubic prostatectomy. Macroscopically the prostate contained multiple circumscribed nodules. Microscopic examination of the tumor showed the appearance of cellular angiofibroma, consisting of bland spindle cells and prominent, hyalinized vessels. The diagnosis was supported by FISH, which revealed monoallelic loss of RB1 /13q14 region, as seen in spindle cell lipoma, (extra-) mammary myofibroblastoma, and cellular angiofibroma. Cellular angiofibromas are rare, benign soft tissue tumours and were never reported in the prostatic gland.