Atherothrombosis‐on‐Chip: A Site‐Specific Microfluidic Model for Thrombus Formation and Drug Discovery (Adv. Biology 7/2022). Issue 7 (15th July 2022)

• Record Type: Journal Article
• Authors: Akther, Fahima; Zhang, Jun; Tran, Huong D. N.; Fallahi, Hedieh; Adelnia, Hossein; Phan, Hoang‐Phuong; Nguyen, Nam‐Trung; Ta, Hang Thu
• Is Part Of: Advanced biology. Volume 6:Issue 7(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-15
• Subjects: Molecular biology -- Periodicals; Systems biology -- Periodicals; Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; 660.6
• DOI: 10.1002/adbi.202270071
• Languages: English
• ISSNs: 2701-0198

Abstract

Abstract : Atherothrombosis‐on‐Chip In article 2101316, Ta and co‐workers conducted a study to mimic the site‐specific atherothrombosis formation on the chip and design a unique microfluidic device with two interconnected microchannels. The device allows the site‐specific introduction of plaque components to develop localized thrombosis and provides a universal platform for studying the crosstalk between blood cells and plaque components. The device is expected to benefit drug testing and carrier designing.