Herbicide Roundup shows toxic effects in nontarget organism Drosophila. Issue 4 (6th April 2022)

• Record Type: Journal Article
• Authors: Strilbytska, Olha M.; Semaniuk, Uliana V.; Strutynska, Tetiana R.; Burdyliuk, Nadia I.; Tsiumpala, Sviatoslav; Bubalo, Volodymyr; Lushchak, Oleh
• Is Part Of: Archives of insect biochemistry and physiology. Volume 110:Issue 4(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-04-06
• Subjects: Drosophila -- herbicide -- lifespan -- oxidative stress -- Roundup; Insects -- Physiology -- Periodicals; Insect biochemistry -- Periodicals; 595.701572
• DOI: 10.1002/arch.21893
• Languages: English
• ISSNs: 0739-4462

Abstract

Abstract: Glyphosate‐based herbicide Roundup, as the most employed herbicide used for multiple purposes in agriculture, adversely affects nontarget organisms. We tested the effects of Roundup applied at larval and adult stages. Roundup caused developmental delay and increased larvae mortality. Roundup treatment reduced hemolymph glucose and glycogen levels in adult flies of both sexes at the highest concentration tested. Sex‐dependent diverse effects were found in catalase and Cu, Zn superoxide dismutase (Cu, Zn‐SOD) activities. Decreased aconitase activity, contents of thiols, and lipid peroxides were found after larval Roundup exposure. Furthermore, chronic exposure to adult flies decreased appetite, body weight, and shortened lifespan. Thus, our results suggest that high concentrations of Roundup are deleterious to both larvae and adults, resulting in a shift of the metabolism and antioxidant defense system in Drosophila melanogaster . Abstract : Roundup caused developmental delay and increased larvae mortality in Drosophila melanogaster . Roundup treatment during development reduced hemolymph glucose and glycogen levels in adult flies of both sexes at the highest concentration tested. Chronic exposure of adult flies decreased appetite, body weight, and shortened lifespan suggesting that high concentrations of Roundup are deleterious to both larvae and adults, resulting in a shift of the metabolism and antioxidant defense system in D. melanogaster .