Left upper lobectomy with combined distal aortic arch and left subclavian artery resection after neoadjuvant chemoradiotherapy for locally advanced lung squamous cell carcinoma. Issue 8 (12th July 2022)

• Record Type: Journal Article
• Authors: Takanashi, Yusuke; Funai, Kazuhito; Kawase, Akikazu; Takahashi, Daisuke; Sekihara, Keigo; Matsubayashi, Yuta; Hayakawa, Takamitsu; Yamashita, Katsushi; Shiiya, Norihiko
• Is Part Of: Respirology case reports. Volume 10:Issue 8(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-12
• Subjects: chemoradiotherapy -- combined aorta resection -- locally advanced lung cancer -- selective cerebral circulation; Respiratory organs -- Diseases -- Periodicals; 616.2005
• DOI: 10.1002/rcr2.994
• Languages: English
• ISSNs: 2051-3380

Abstract

Abstract: T4 locally advanced non‐small cell lung cancer (NSCLC) is a heterogeneous group with a great variety of involved organs and is associated with a poor prognosis. However, appropriately selected patients benefit from surgical resection. The surgical indication must be carefully considered based on the risk–benefit between high surgical stress and expected prognosis, particularly in cases with probable aortic involvement. Here, we report a long‐term survival case of left upper lobe squamous cell carcinoma, in which lobectomy and combined distal aortic arch and left subclavian artery resection achieved a complete resection after induction chemoradiotherapy (CRT). Appropriate patient selection considering expected prognosis, induction CRT and complete resection under well‐planned cardiopulmonary bypass are essential to achieve a long‐term survival on T4 NSCLC with a probable aortic involvement Abstract : We report a long‐term survival case of left upper lobe squamous cell carcinoma, in which lobectomy and combined distal aortic arch and left subclavian artery resection achieved a complete resection after induction chemoradiotherapy (CRT). Appropriate patient selection considering expected prognosis, induction CRT and complete resection under well‐planned cardiopulmonary bypass are essential to achieve a long‐term survival on T4 non‐small cell lung cancer with a probable aortic involvement.