Pityriasis rosea in pregnancy: A case series and literature review. (26th May 2022)

• Record Type: Journal Article
• Authors: Wenger‐Oehn, Lena; Graier, Thomas; Ambros‐ Rudolph, Christina; Müllegger, Robert; Bittighofer, Christina; Wolf, Peter; Hofer, Angelika
• Is Part Of: Journal der Deutschen Dermatologischen Gesellschaft. Volume 20:Number 7(2022)
• Page Start: 953
• Page End: 959
• Publication Date: 2022-05-26
• Subjects: Skin -- Diseases -- Periodicals; Dermatology -- Periodicals; 616.5005
• DOI: 10.1111/ddg.14763
• Languages: English
• ISSNs: 1610-0379

Abstract

Summary: Background and objective: Pityriasis rosea (PR), a common skin disease in young adults, may adversely affects the course of pregnancy and the unborn child. Patients and methods: Data from forty‐six pregnant women with PR seen in the dermatological university clinic between 2003 and 2018 were analyzed and compared with patient data (n = 53) from previously published studies to determine the incidence and risk factors for an unfavorable pregnancy outcome after PR infection. Results: Unfavorable pregnancy outcomes (defined as miscarriage, preterm delivery before week 37 of gestation, or birth weight < 2, 500 g) were significantly less frequent in our study population than in a pooled cohort obtained from previously published studies (10.9 % vs. 39.6 %; P = 0.0012). Analysis of pooled data from our study and from previous studies revealed that the week of pregnancy at onset of PR was inversely associated with an unfavorable outcome (odds ratio [OR] = 0.937; 95 % CI 0.883 to 0.993). In addition, duration of PR (OR = 1.432; 95 % CI 1.129 to 1.827), additional extracutaneous symptoms (OR = 4.112; 95 % CI 1.580 to 10.23), and widespread rash distribution (OR 5.203, 95 % CI 1.702 to 14.89) were directly associated with unfavorable outcome. Conclusion: In most cases, PR does not influence pregnancy or birth outcomes.