DNA Tetrahedron Framework Guided Conjugation and Assembly of Gold Nanoparticles. Issue 7 (13th July 2022)

• Record Type: Journal Article
• Authors: He, Wei; Zhao, Yan; Xing, Shu; Zhang, Yinan; Wang, Lihua; Liu, Huajie
• Is Part Of: ChemPlusChem. Volume 87:Issue 7(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-13
• Subjects: DNA nanotechnology -- DNA tetrahedra -- gold nanoparticles -- nanostructures -- self-assembly; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cplu.202200159
• Languages: English
• ISSNs: 2192-6506

Abstract

Abstract: Au nanoparticles (AuNPs) have been extensively used to assemble programmable structures that feature various functions. One central challenge of precisely directed assembly is to make valence‐programmable building blocks. Herein, we use the DNA tetrahedron framework to stoichiometrically conjugate to Au nanoparticles, which results in monovalent building blocks at nanometer scale. We further fabricated high‐order Au‐tetrahedron structures to verify the ability of the blocks for building assemblies. These structures represent an exploration of an avenue to monovalent AuNPs, and provide the feasibility of precisely manipulating nanoparticles into prescribed assemblies. Abstract : A DNA tetrahedron ‐guided ‐assembly strategy has been developed for the fabrication of monovalent building blocks by stoichiometrically conjugation of programmable DNA tetrahedrons to Au nanoparticles (AuNPs). The monovalent AuNPs was used to assemble high‐order AuNPs structures. The tetrahedron on the surface of AuNPs could be observed by the AFM, and high‐order tetrahedron‐AuNPs structures were characterized by TEM analysis