How to approach adult patients with asymptomatic esophageal eosinophilia. Issue 1 (3rd October 2020)

• Record Type: Journal Article
• Authors: Schreiner, Philipp; Biedermann, Luc; Greuter, Thomas; Wright, Benjamin L; Straumann, Alex
• Is Part Of: Diseases of the esophagus. Volume 34:Issue 1(2021)
• Publication Date: 2020-10-03
• Subjects: eosinophilic esophagitis -- eosinophilic gastrointestinal disorders -- eosinophils; Esophagus -- Diseases -- Periodicals; 616.32
• DOI: 10.1093/dote/doaa105
• Languages: English
• ISSNs: 1120-8694

Abstract

Summary: As the awareness among gastroenterologists regarding endoscopic features suggesting eosinophilic esophagitis is increasing, individuals without symptoms of esophageal dysfunction are increasingly being found to have esophageal eosinophilia on biopsies performed during upper gastrointestinal endoscopies. However, the course of disease and the management of these asymptomatic individuals with esophageal eosinophilia remain elusive. In this review, we propose a definition of asymptomatic individuals with esophageal eosinophilia and discuss the prevalence, risk factors, and course of disease of this specific patient group. Furthermore, we have established a diagnostic and therapeutic pathway based on the most recent available data.