Survival Advantage of Lymphadenectomy in Patients with Ovarian Cancer. (9th August 2022)

• Record Type: Journal Article
• Authors: Ignatov, Atanas; Hassan, Sheref Salim; Ivros, Stylianos; Papathemelis, Thomas; Ignatova, Zoya; Eggemann, Holm
• Is Part Of: Cancer investigation. Volume 40:Number 7(2022)
• Page Start: 621
• Page End: 628
• Publication Date: 2022-08-09
• Subjects: Ovarian cancer -- lymphadenectomy -- early stage -- debulked; Cancer -- Periodicals; Oncology -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- Periodicals; 616.994
• DOI: 10.1080/07357907.2022.2067558
• Languages: English
• ISSNs: 0735-7907

Abstract

Abstract: We investigated the survival effect of lymphadenectomy in ovarian cancer. The five-year progression-free and overall survival in early-stage ovarian cancer were not affected. Preliminary, unadjusted analysis in advanced ovarian cancer suggested an improvement in survival. However, after adjusting for other factors, e.g. ECOG performance status and patients' age, this survival advantage vanished. Our analysis suggests that systemic pelvic and para-aortic lymphadenectomy was not associated with an improvement of the progression-free and overall survival of patients with optimally debulked ovarian cancer.