Cryoballoon ablation beyond pulmonary vein isolation in the setting of persistent atrial fibrillation. (4th May 2022)

• Record Type: Journal Article
• Authors: Miraglia, Vincenzo; Bisignani, Antonio; Pannone, Luigi; Iacopino, Saverio; Chierchia, Gian-Battista; de Asmundis, Carlo
• Is Part Of: Expert review of medical devices. Volume 19:Number 5(2022)
• Page Start: 431
• Page End: 439
• Publication Date: 2022-05-04
• Subjects: Atrial arrhythmias -- atrial fibrillation -- cryoballoon -- cryoablation -- non pulmonary vein triggers; Medical instruments and apparatus -- Periodicals; 610.28
• DOI: 10.1080/17434440.2022.2096437
• Languages: English
• ISSNs: 1743-4440

Abstract

ABSTRACT: Introduction: Catheter ablation has been demonstrated to be a safe and an effective treatment for drug resistant atrial fibrillation (AF); electrical isolation of pulmonary veins (PVI) is the main strategy in paroxysmal AF, since pulmonary vein triggers have a pivotal role in its pathogenesis; non-paroxysmal AF is a complex arrhythmia that results from the interplay of a substrate, namely AF-induced electrical and structural atrial remodeling, and a trigger that can be often found outside pulmonary veins, namely non-pulmonary veins triggers. Areas covered: The aim of this review is to provide a state-of-the-art overview of non-pulmonary veins triggers with special focus on cryoballoon (CB) catheter ablation. Expert opinion: Besides PVI, CB catheter ablation of non-pulmonary veins triggers is a novel and promising strategy for non-paroxysmal AF.