Transfer hydrogenation of ketone; an in situ approach toward an eco-friendly reduction. Issue 31 (7th July 2022)

• Record Type: Journal Article
• Authors: Onisuru, Oluwatayo Racheal; Fapojuwo, Dele Peter; Oseghale, Charles O.; Alimi, Oyekunle Azeez; Meijboom, Reinout
• Is Part Of: RSC advances. Volume 12:Issue 31(2022)
• Page Start: 19890
• Page End: 19900
• Publication Date: 2022-07-07
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d2ra02701a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : The use of water as a solvent in chemical reactions has recently been brought to public attention, especially in the exploration of eco-friendly procedures. Abstract : The use of water as a solvent in chemical reactions has recently been brought to public attention, especially in the exploration of eco-friendly procedures. It is readily available, abundantly accessible, non-toxic, non-flammable, and at a low cost. As opposed to the previous limitation of reactant solubilities associated with aqueous media, a hydrogel such as a hydroxypropyl methylcellulose (HPMC) solution can significantly improve the reactant solubility. This investigation employed water and HPMC as the reaction solvent, and the reaction medium viscosity was impressively enhanced. Silica-supported Pd particles (Pd@SiO2 ) were synthesized and effectively catalyzed the reduction of acetophenone in the presence of sodium borohydride (NaBH4 ) as the hydrogen source. The conversion of acetophenone to 1-phenyl ethanol remained at a very high value of >99.34% with 100% selectivity towards 1-phenyl ethanol.