Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o‐Carborane (C2B10H12) Derivatives Incorporating DNA Fragments. Issue 43 (8th September 2015) - Janczak, Slawomir
Abstract: A synthetic strategy for functionalization of the three vertices of o ‐carborane and the attachment of the obtained triped to the solid support was developed. Further functionalization of the triped with short DNA sequences by automated DNA synthesis was achieved. The proposed methodology is a first example of boron cluster chemistry on a solid support opening new perspectives in boron cluster functionalization. Abstract : A synthetic strategy for the functionalization of two boron and one carbon vertices of o ‐carborane was developed. The obtained o ‐carborane triped was used for a solid support synthesis of a boron cluster–DNA construct (see figure).