Solvent-free continuous flow hydrogenation of N-methylpyrrolidone to N-methylpyrrolidine catalyzed by bimetallic Pt/V on HAP. Issue 14 (9th June 2022)

• Record Type: Journal Article
• Authors: Gao, Pengxiang; Liu, Song; Yang, Jitao; Zhao, Dishun; Liu, Qingbin
• Is Part Of: Catalysis science & technology. Volume 12:Issue 14(2022)
• Page Start: 4605
• Page End: 4612
• Publication Date: 2022-06-09
• Subjects: Catalysis -- Periodicals; 541.395
• DOI: 10.1039/d2cy00581f
• Languages: English
• ISSNs: 2044-4753

Abstract

Abstract : The continuous flow hydrogenation of N -methylpyrrolidone which catalyzed by Pt/V/HAP (Pt/V molar ratio = 1 : 0.5) was achieved running for 100 h with solvent-free, and the N -methylpyrrolidine yield was above 85.21%. Abstract : Herein, solvent-free continuous flow bimetallic Pt/V catalytic hydrogenation of N -methylpyrrolidone (NMP) to prepare N -methylpyrrolidine (NMPD) was developed. The yield of NMPD was as high as 89.41%, and the best weight hourly space velocity was 1.2 h −1 under the optimal reaction conditions, which were screened by the response surface methodology. The catalysts with different ratios of Pt and V supported on hydroxyapatite (HAP) were prepared and evaluated for activity for the hydrogenation of NMP. The best catalyst proportion was Pt/V = 1 : 0.5 on HAP, which was characterized by STEM-EDS, ICP-OES, BET, XPS, and PSD analyses. It was shown that polyvalent Pt and V were highly dispersed on HAP and the synergistic effect between Pt and V species contributed to the excellent catalytic performance. More importantly, the catalyst stability was excellent and after running for 100 h, the yield remained at 85.21%. Significantly, this solvent-free continuous flow catalytic hydrogenation of an amide provides a green, efficient, low-cost and environmentally friendly process for the synthesis of NMPD.