Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance. Issue 57 (21st June 2022)
- Record Type:
- Journal Article
- Title:
- Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance. Issue 57 (21st June 2022)
- Main Title:
- Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance
- Authors:
- Fletcher, N. L.
Prior, A.
Choy, O.
Humphries, J.
Huda, P.
Ghosh, S.
Houston, Z. H.
Bell, C. A.
Thurecht, K. J. - Abstract:
- Abstract : A pre-targeting approach to preserve the stealth surface chemistry of PEGylated nanomedicines during circulation is demonstrated. Abstract : Pre-targeting of bispecific antibodies is probed to enhance tumour retention while limiting clearance of administered multifunctional branched PEGylated nanomedicines. The temporal influence of pre-targeting on polymer interaction with tumour cells and tissue is explored using in vitro assays through to preclinical validation.
- Is Part Of:
- Chemical communications. Volume 58:Issue 57(2022)
- Journal:
- Chemical communications
- Issue:
- Volume 58:Issue 57(2022)
- Issue Display:
- Volume 58, Issue 57 (2022)
- Year:
- 2022
- Volume:
- 58
- Issue:
- 57
- Issue Sort Value:
- 2022-0058-0057-0000
- Page Start:
- 7912
- Page End:
- 7915
- Publication Date:
- 2022-06-21
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d2cc02443h ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 22591.xml