Solitary neurofibroma of the larynx: a diagnostic challenge. Issue 1 (18th January 2021)

• Record Type: Journal Article
• Authors: Cunha, Bruno; Pacheco, Ricardo; Fonseca, Isabel; Borges, Alexandra
• Is Part Of: BMJ case reports. Volume 14:Issue 1(2021)
• Publication Date: 2021-01-18
• Subjects: ear -- nose and throat/otolaryngology -- head and neck cancer -- radiology -- head and neck surgery -- peripheral nerve disease; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2020-236682
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Solitary neurofibromas of the larynx are extremely rare, with a total of 15 cases described in the literature. Nonetheless, acquaintance with this diagnosis is important, as misdiagnoses can have negative consequences. Presenting symptoms are non-specific and depend on tumour size and location. As well-defined submucosal masses with a broad differential diagnosis, they remain a clinical and radiological challenge. While some characteristics might favour a benign nature and subtle signs might help narrow the differential diagnosis, imaging alone is not sufficient for differentiation and definitive diagnosis requires a biopsy. Complete surgical resection and long-term follow-up is indicated. We share our experience on a case of a solitary laryngeal neurofibroma in a middle-aged woman, presenting with a large well-defined paraglottic lesion.