Response to: Low molecular weight guluronate: A potential therapies for inspiratory muscle dysfunction and restrictive lung function impairment in congenital heart disease by Guiyuan He, Ruiting Zhou, Tingyuan Huang, Fanjun Zeng1Original work: Spiesshoefer et al. Impact of congenital heart disease on respiratory muscle function – are immune inflammatory response and exercise intolerance linked to it? International Journal of Cardiology (2020) 318: 45–51. (15th September 2022) - Spiesshoefer, Jens