Image quality of the CAIPIRINHA-Dixon-TWIST-VIBE technique for ultra-fast breast DCE-MRI: Comparison with the conventional GRE technique. Issue 129 (August 2020)

• Record Type: Journal Article
• Authors: Hao, Wen; Peng, Weijun; Wang, Cuiyan; Zhao, Bin; Wang, Guangbin
• Is Part Of: European journal of radiology. Issue 129(2020)
• Publication Date: 2020-08
• Subjects: Breast -- DCE -- MRI -- CDT-VIBE -- GRE; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2020.109108
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: CDT-VIBE was used for high tempo-spatial resolution breast DCE-MRI. The image quality of CDT-VIBE was compared with conventional GRE sequence. Compared with GRE, CDT-VIBE showed more PAT artifacts and blurry structures. The overall image quality of CDT-VIBE was lower than that of conventional GRE. Morphological characterizations on CDT-VIBE and GRE images were comparable. Abstract: Purpose: The aim of this study was to evaluate image quality of the CAIPIRINHA-Dixon-TWIST-Volume-Interpolated Breath-hold Examination (CDT-VIBE) technique for ultra-fast breast dynamic contrast enhanced (DCE) MRI with respect to conventional Gradient-Recalled Echo (GRE) technique. Methods: A total of 58 patients underwent a DCE-MRI based on CDT-VIBE sequence (temporal resolution: 11.9 s), immediately followed by 1 phase of a conventional T1 weighted GRE sequence (acquisition time: 68 s). The Signal-to-Noise Ratio (SNR) on phantom images, lesion/parenchyma signal ratio (LPSR), image quality, and morphological characterization were compared between the last phase of CDT-VIBE and conventional GRE images. The image quality was assessed by visual grading analysis (VGA). Reader agreement was assessed using Kappa analysis. Results: There was no significant difference in SNR (phantom) or LPSR (patient) between CDT-VIBE and conventional GRE images (P > 0.05). Significant parallel acquisition technique (PAT) noise and mild blurriness was observed on CDT-VIBE images. Visual grading analysis (VGA) confirmed significantly worse ratings for CDT-VIBE compared to the conventional GRE sequence in terms of PAT noise, lesion's internal feature clarity, and therefore overall image quality (area under contrast curve [AUC] values: 0.578 ‒ 0.764, P < 0.05), but edge sharpness and lesion conspicuity were equivalent (P > 0.05). Kappa analysis revealed good agreement on image quality scores (к = 0.725 ‒ 0.908) and on morphologic terms (к = 0.745–1.000). Conclusion: The CDT-VIBE sequence provides excellent spatial resolution and adequate image quality in ultra-fast breast DCE-MRI. Further improvement in PAT noise and internal structure blurriness may be necessary.