Are We missing out the role of oxytocin in overactive bladder syndrome?. (4th December 2020)

• Record Type: Journal Article
• Authors: Canguven, Onder; Talib, Raidh
• Is Part Of: Aging male. Volume 23:Number 5(2020)
• Page Start: 700
• Page End: 704
• Publication Date: 2020-12-04
• Subjects: Muscarinic receptor -- neurogenic bladder -- contraction -- treatment -- detrussor muscle -- bladder neck; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.1080/13685538.2019.1577376
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Overactive bladder (OAB) is characterized by the storage symptoms of urgency with or without urgency incontinence. Although there is no clear cause of this idiopathic disease, overall prevalence of OAB symptoms in individuals aged 40 years old is more than 15%. Oxytocin, which is one of the most powerful contracting neuropeptide, was also shown to exhibit high intrinsic contractile activity on detrusor muscle. Oxytocin receptor antagonists that inhibit of bladder activity might offer new insights into the treatment of OAB.