The correlation between atherogenic indexes and erectile dysfunction. (4th December 2020)

• Record Type: Journal Article
• Authors: Culha, Mehmet Gokhan; Canat, Lutfi; Degirmentepe, Recep Burak; Albayrak, Ahmet Tevfik; Atalay, Hasan Anil; Merder, Erkan; Ariman, Ahmet; Altunrende, Fatih
• Is Part Of: Aging male. Volume 23:Number 5(2020)
• Page Start: 1232
• Page End: 1236
• Publication Date: 2020-12-04
• Subjects: Atherosclerosis -- atherogenic index -- Castelli's risk index -- erectile dysfunction; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.1080/13685538.2020.1749996
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Aside from the ordinary plasma lipid level measurements, the ratios based on individual plasma lipid levels such as atherogenic index of plasma (AIP), Castelli's risk index 1/2 (CRI-1/2), and atherogenic coefficient (AC) are the novel parameters to evaluate the patients with a high risk of CVD. In this study, we aim to evaluate the relationship between AIP, AC, and CRI-1/2 with increased risk of ED. Between April 2018 and February 2019, 253 patients, who were diagnosed as a vasculogenic ED in our clinic, were enrolled in the study. While the first group ( n = 134) consisted of patients with moderate and mild ED (IIEF-EF: 17–30), the second group ( n = 119) consisted of patients with severe ED. In addition to the mean values of lipid parameters; CRI-1 (total cholesterol/HDL), CRI-2 (LDL/HDL) AIP (log10(triglycerides/HDL), and AC (non-HDL/HDL) were calculated. The mean age was 44.02 ± 10.41 (24–70), and the mean BMI was 27.80 ± 4.12 (18.52 ± 41.97). However, CRI-1 and AIP values were found to be higher in the severe ED group compared to the mild ED group (CRI-1: 4.50 ± 1.47, 4.88 ± 1.30; p = .039; AIP: 0.489 ± 0.315, 0.617 ± 0.283; p = .007). Our results demonstrated that CR-1 and AIP have a positive correlation with the severity of ED. Moreover, we can suggest that patients with higher CR-1 and AIP values are likely to have more severe ED in the future.