Two Cases of Endometrial Cancer in Twin Sisters with Myotonic Dystrophy. (9th August 2016)

• Record Type: Journal Article
• Authors: Koh, Ezra Y.; van Kesteren, Paul J. M.
• Other Names: Fagotti Anna Academic Editor.
• Is Part Of: Case reports in obstetrics and gynecology. Volume 2016(2016)
• Publication Date: 2016-08-09
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; Obstetrics; Gynecology; Genital Diseases, Female; Generative organs, Female -- Diseases; Gynecology; Obstetrics; Electronic journals; Periodicals; Periodicals; 618
• DOI: 10.1155/2016/9737014
• Languages: English
• ISSNs: 2090-6684

Abstract

Abstract : We describe two cases of endometrial cancer (EC) occurring in nulligravid twin sisters with myotonic dystrophy. Both tested negative for Lynch syndrome and both were treated with laparoscopic hysterectomy with bilateral salpingooophorectomy and adjuvant radiotherapy. Although EC tends to run in families, the diagnosis in itself is not considered sufficient cause for screening or prophylactic measures in close relatives. However, the presence of additional risk factors, such as nulligravidity and myotonic dystrophy in the underlying cases, may call for extra vigilance in first-degree family members.