Serum bicarbonate level improves specificity of Berlin Sleep Questionnaire for obstructive sleep apnea. (4th December 2020)

• Record Type: Journal Article
• Authors: Dursun, Mazlum; Selimoğlu Şen, Hadice; Yılmaz, Süreyya; Demir, Melike; Kırbaş, Gökhan; Taylan, Mahşuk
• Is Part Of: Aging male. Volume 23:Number 5(2020)
• Page Start: 1480
• Page End: 1486
• Publication Date: 2020-12-04
• Subjects: Berlin Sleep Questionnaire -- obstructive sleep apnea -- arterial blood gas; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.1080/13685538.2020.1801623
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Several questionnaires have been developed to assist the diagnostic process in obstructive sleep apnea syndrome (OSAS). Berlin Sleep Questionnaire (BSQ) represents a validated screening tool for OSAS. Totally 450 patients admitted to the Sleep Center at Dicle University Medical Faculty were included prospectively. A risk analysis was performed for presence of OSAS using the BSQ. Arterial blood gas measurements were performed including bicarbonate (HCO3) level. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of BSQ for presence of OSAS and severe OSAS were determined. In patients with arterial HCO3 >24.94 mEq/L; sensitivity, specificity, PPV and NPV, of the BSQ were 93.04, 57.1, 98.3, and 23.5%, respectively. The addition of arterial HCO3 value increased the sensitivity of the BSQ in detecting OSAS patients. Although the cost of sleep studies is high for false positives from the BSQ plus arterial HCO3 level, this cost should be compared with the loss of work efficiency and severe healthcare costs of undiagnosed cases in the future. Therefore, finding possible OSAS cases in primary care health centers is important and adding serum HCO3 value to BSQ questionnaire may contribute to this topic.