Levodopa-Responsive Early-Onset Parkinsonism in Down Syndrome. (15th February 2018)

• Record Type: Journal Article
• Authors: Palat, Padmini; Hickey, Francis; Patel, Lina; Sannar, Elise
• Other Names: Berlit Peter Academic Editor.
• Is Part Of: Case reports in neurological medicine. Volume 2018(2018)
• Publication Date: 2018-02-15
• Subjects: Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurology; Nervous System Diseases; Nervous system -- Diseases; Neurology; Electronic journals; Periodicals; Periodicals; 616.8
• DOI: 10.1155/2018/2314791
• Languages: English
• ISSNs: 2090-6676

Abstract

Abstract : Individuals with Down syndrome (DS) can develop Alzheimer's disease as early as 30 to 40 years old, but parkinsonism is rarely described. We report on a 20-year-old woman with Down syndrome and parkinsonism who responded dramatically to carbidopa-levodopa. We propose that the occurrence of parkinsonism in individuals with DS may be underreported. Recognizing and treating this condition may improve quality of life.