Voriconazole-Induced Periostitis Mimicking Chronic Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation. (14th June 2016)

• Record Type: Journal Article
• Authors: Sweiss, Karen; Oh, Annie; Rondelli, Damiano; Patel, Pritesh
• Other Names: Domingo Pere Academic Editor.
• Is Part Of: Case reports in infectious diseases. Volume 2016(2016)
• Publication Date: 2016-06-14
• Subjects: Communicable diseases -- Periodicals; Communicable diseases -- Case studies -- Periodicals; Communicable Diseases; Infectious Disease Medicine; Communicable diseases; Electronic journals; Periodicals; Case studies; Periodicals; 616.9
• DOI: 10.1155/2016/3242196
• Languages: English
• ISSNs: 2090-6625

Abstract

Abstract : Voriconazole is an established first-line agent for treatment of invasive fungal infections in patients undergoing allogeneic stem cell transplantation (ASCT). It is associated with the uncommon complication of periostitis. We report this complication in a 58-year-old female undergoing HSCT. She was treated with corticosteroids with minimal improvement. The symptoms related to periostitis can mimic chronic graft-versus-host disease in patients undergoing HSCT and clinicians should differentiate this from other diagnoses and promptly discontinue therapy.