Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis. (26th November 2017)

• Record Type: Journal Article
• Authors: Cromlin, H.; Rodriguez-Villalobos, H.; Deplano, A.; Duprez, T.; Hantson, P.
• Other Names: Marra Alexandre R. Academic Editor.
• Is Part Of: Case reports in infectious diseases. Volume 2017(2017)
• Publication Date: 2017-11-26
• Subjects: Communicable diseases -- Periodicals; Communicable diseases -- Case studies -- Periodicals; Communicable Diseases; Infectious Disease Medicine; Communicable diseases; Electronic journals; Periodicals; Case studies; Periodicals; 616.9
• DOI: 10.1155/2017/8976754
• Languages: English
• ISSNs: 2090-6625

Abstract

Abstract : Spontaneous or nosocomial Escherichia coli meningitis remains rare in healthy adults but is still carrying a high mortality rate despite adapted antimicrobial treatment for susceptible strains. A 39-year-old woman was admitted to the hospital with severe subarachnoid haemorrhage complicated by acute hydrocephalus. On hospital day 10, she developed Streptococcus anginosus septicaemia and urinary tract infection due to a multisensitive strain of E. coli . This infection was successfully controlled by antimicrobial therapy. As a late complication in the neurosurgical ward (day 39), she developed fever, alteration of consciousness, and shock, leading to the diagnosis of bacterial meningitis. The culture of blood, cerebrospinal fluid, and urine grew positive for a multisensitive E. coli . The strain was identified as O117:K52:H, a serotype that was until now never associated with acute meningitis or brain abscesses. The source appeared to be the urinary tract with the demonstration of acute pyelonephritis. The patient died on day 94 from delayed complications of multiple brain abscesses.