Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm. (2nd September 2014)

• Record Type: Journal Article
• Authors: Zielinska, Patrycja; Markiewicz, Miroslaw; Dzierzak-Mietla, Monika; Koclega, Anna; Helbig, Grzegorz; Kyrcz-Krzemien, Slawomira
• Other Names: Micci Francesca Academic Editor.
• Is Part Of: Case reports in oncological medicine. Volume 2014(2014)
• Publication Date: 2014-09-02
• Subjects: Oncology -- Periodicals; Tumors -- Periodicals; Oncology -- Case studies -- Periodicals; Neoplasms; Oncology; Tumors; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.994
• DOI: 10.1155/2014/512928
• Languages: English
• ISSNs: 2090-6706

Abstract

Abstract : Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disorder in the same patient is extremely rare. In the present report, a case of an 81-year-old man who was diagnosed with chronic lymphocytic leukemia and concomitant essential thrombocythemia is presented. We describe the morphologic, immunophenotypic, cytogenetic, and molecular findings in this patient. We also review the current literature.