Massive Intestinal Bleeding in an Adult with IgA Vasculitis Treated with Intravenous Immunoglobulin. (14th June 2022)

• Record Type: Journal Article
• Authors: Nassereddin, Ibrahim; Kenig, Ariel; Ishay, Yuval; Lehmann, Hillel; Hurvitz, Noa; Elkhateeb, Narmine; Gelman, Ram; Ratz, Yael; Sarig, Inon; Burstain, Ido; Benshushan, Stephanie; Kharouf, Fadi
• Other Names: Dunne James V. Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2022(2022)
• Publication Date: 2022-06-14
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2022/9694911
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : We report the case of a 29-year-old adult presenting with severe IgA vasculitis, with cutaneous, urologic, and renal manifestations. The late appearance of severe gastrointestinal bleeding dominated the clinical picture, necessitating the administration of tens of units of packed cells and the augmentation of the immunosuppressive protocol. It was not until therapy with intravenous immunoglobulin (IVIG) was introduced that the massive bleeding was controlled. We herein discuss the patient's presentation, the gastrointestinal manifestations of IgA vasculitis, the recommended treatments, and the existent evidence about IVIG therapy.