Dentinogenic ghost cell tumor – Case report of a rare entity. (April 2021)

• Record Type: Journal Article
• Authors: Salgado, Inês; Vilares, Miguel; Nogueira, Ricardo; Rito, Miguel; Rosa, Filipa; Gomes, Pedro
• Is Part Of: International journal of surgery case reports. Volume 81(2021)
• Publication Date: 2021-04
• Subjects: Dentinogenic ghost cell tumor -- Odontogenic tumor -- Maxillectomy -- Head and neck -- Case report; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2021.105651
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: There are several entities that can cause a head and neck expansive bone lesion and it's important to consider a neoplastic cause. This report presents the case of a patient with a central dentinogenic ghost cell tumor. The patient underwent an extensive local resection and 10 months after surgery there are no signs of local recurrence. Due to its rarity, increased clinical awareness about this entity is essential to optimize the approach of these patients. Abstract: Introduction: Dentinogenic ghost cell tumor (DGCT) is an entity with about 60 cases reported in the literature. It is a benign odontogenic tumor, despite being locally invasive and associated with a risk of local recurrence. Presentation of case: A 47-year-old woman presented with a 2-year-old expansive bone lesion. Radiologically, a multilocular mass was identified in the left superior maxilla, compatible with a tumor of odontogenic origin. She was submitted to an extended resection, and the histology was consistent with a DGCT. Discussion: Central DGCT affects mainly male patients between the fourth and sixth decades, with a predilection for the posterior portion of the jaws. The symptoms are unspecific, and a vast percentage of patients is asymptomatic. Radiographically a unilocular feature is commonly found, unlike this case. The recommended treatment is extended local resection due to its high recurrence rate. Conclusion: Due to its rarity, knowledge of this entity is necessary for a better diagnostic and therapeutic guidance.